Sironko is the largest metropolitan area in Sironko District of the Eastern Region of Uganda and the site of the district headquarters. Sironko li…Sironko is the largest metropolitan area in Sironko District of the Eastern Region of Uganda and the site of the district headquarters. Sironko lies 25 kilometres northeast of the city of Mbale on the highway between Mbale and Moroto. It is located 245 kilometres northeast of Kampala, Uganda's capital and largest city. The coordinates of the town are 01°13'50.0"N, 34°14'53.0"E. Sironko sits at an average elevation of 1,184 metres above mean sea level.