Characterization of the first class D β-lactamases in Gram-positive bacteria, including the Bacillaceae family, shows that one, BPU-1, is capable of hydrolyzing a wide variety of β-lactam ...

AmpC β-lactamases are chromosomally encoded cephalosporinases intrinsic to all A. baumannii. Usually, such β-lactamases have a low level of expression that does not cause clinically appreciable ...

Hamrick JC, Docquier J-D, Uehara T, et al. VNRX-5133 (taniborbactam), a broad-spectrum inhibitor of serine- and metallo-β-lactamases, restores activity of cefepime in Enterobacterales and ...

Table 3. Genetic environment of the VIM-type metallo-β-lactamases associated with class 1 integrons. VIM Gene cassette(s) between 5'-CS and 3'-CS ...

AmpC β-lactamases are chromosomally encoded in many bacterial species. Their overexpression can lead to resistance to most β-lactam antibiotics, causing therapeutic failure. Transmissible plasmids ...

The combination of aztreonam with avibactam restores aztreonam’s activity against bacteria that co-produce MBLs and other β-lactamases and, if approved, could offer a much-needed safe and ...

Metallo-beta-lactamases were the most frequently identified carbapenem resistance mechanism among Enterobacterales isolates in IHMA global surveillance. August 14, 2023 07:00 AM Eastern Daylight Time.

Table 3. Genetic environment of the VIM-type metallo-β-lactamases associated with class 1 integrons. VIM Gene cassette(s) between 5'-CS and 3'-CS ...

metallo-β-lactamases strip, PCR-based techniques and DNA sequencing are all required to identify the metallo-β-lactamases genes. The diversity of integron structures suggests different origins and ...

metallo-β-lactamases strip, PCR-based techniques and DNA sequencing are all required to identify the metallo-β-lactamases genes. The diversity of integron structures suggests different origins and ...