Therefore, the HIF field seems to be ready for expanded searches for specific regulating pharmaceuticals, and it can be predicted that, just as the increasing number of identified AHR functions ...

Metabolic changes induced by hypoxia and extracellular ATP, acting through the transcription factors HIF1-α and AHR, regulate the differentiation of type 1 regulatory (Treg1) cells. Our ...

CHICAGO — A novel oral aryl hydrocarbon receptor inhibitor appeared well tolerated and safe among a small cohort of patients with advanced solid tumors, according to phase 1 study results ...