All mitochondria retain core genomes of their own, which are necessary for the control of membrane potential across a circumscribed area of membrane, enabling a 104-105-fold increase in the total area ...

Mitochondrial dysfunction, including decreased mitochondrial respiration and increased mitochondrial stress, is associated with many major human diseases and casual to many pathological defects.

A paper by scientists affiliated with the University of São Paulo highlights new discoveries regarding the mechanisms of oxidative phosphorylation involved in ATP production. Recent studies have ...

If there’s one thing that most folks will remember from even just high school biology class, it’s that the mitochondria is the “powerhouse of the cell.” Why? Because it creates ATP, a cellular ...

A team of researchers has uncovered a previously unrecognized role of mitochondrial protein synthesis in the maintenance of intracellular iron distribution. Disruption of this process was found to ...

A defect in mitochondrial tRNA modification impairs the proper formation of mitochondrial OXPHOS complexes, which results in iron transmigration from mitochondria to cytosol. Excess cytosolic iron ...