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Over the years, there has been an increasing demand for an effective and cost-efficient drug discovery process. The study of ...

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The use of nonsteroidal anti-inflammatory drugs (NSAIDs), acetylsalicylic acid (ASA), and cyclo-oxygenase 2 selected inhibitors is associated with an increased frequency of dyspepsia and ...

Figure 1. The formation of AA and LA metabolites (ASA-COX―acetylsalicylic acid (aspirin) cyclooxygenase, PGG―prostaglandin G, LOX―lipoxygenase, HETE―hydroxyeicosatetraenoic acids ...

Management. Long-term immunosuppressive treatment with azathioprine (150 mg/day) and prednisolone (10 mg/day), and inhibition of thrombocyte function with acetylsalicylic acid (100 mg/day).

Since then, aspirin, or acetylsalicylic acid (ASA), has remained one of the world's safest, least expensive, and most consumed analgesics. In the United States, the annual consumption of aspirin ...