EAGLE provided a substantial increase in power over standard methods; yet the overall number of associations remained modest, indicating that GxE interaction effects on gene expression are not ...

Gene interaction models favouring parent-of-origin ... If the maintenance of beneficial allelic combinations favours the evolution of imprinting as highlighted in this model, we may further ...

The new "allelic drive," described April 9 in Nature Communications, is equipped with a guide RNA (gRNA) that directs the CRISPR system to cut undesired variants of a gene and replace it with a ...

The new "allelic drive," described April 9 in Nature Communications, is equipped with a guide RNA (gRNA) that directs the CRISPR system to cut undesired variants of a gene and replace it with a ...

part of a gene sequence can be copied between different genes on the same DNA molecule – this is known as non-allelic gene conversion. This process has been linked to the evolution of important ...

Dosage compensation is required to adjust the allelic expression of X-linked genes to compensate for differences in gene dosage between the sexes. In mammals, one of the X chromosomes is turned ...