The androgen receptor is the primary driver of the initiation and growth of prostate cancer, the second-leading cause of death in men. Looking to have a better understanding of how the androgen ...

“The androgen receptor doesn’t follow the rules,” Dr. Wasmuth says. The different three-dimensional shapes created by these movements also allow the androgen receptor to interact with other proteins ...

New androgen receptor structure suggests prostate cancer treatment options. Baylor College of Medicine. Journal Molecular Cell DOI 10.1016/j.molcel.2020.06.031 ...

The androgen receptor is simply more versatile in the sets of genes it can turn on compared with other nuclear receptors. In fact, recent findings even suggest that it can affect T cell responses ...

The androgen receptor in prostate cancer cells can activate different sets of genes depending on whether it binds with an androgen hormone or an antiandrogen drug, according to a new study. The ...

The androgen receptor is a key transcriptional factor for the proper sex development -- especially in males -- and the physiological balance of all the tissues that express this receptor. The ...

Sustained androgen-receptor signaling is a major driver of castration-resistant prostate cancer, owing to the contributions from the increased expression of the androgen receptor 2 and an acquired ...

Anti-androgen drugs work by blocking the effects of androgens, such as testosterone.They do this by binding to proteins called androgen receptors. They bind to these receptors so that androgens ...

An androgen receptor Wikimedia Commons W hen transgender men transition, their risk for breast cancer tends to plummet and look more like the breast cancer risk for cisgender men, excluding those ...

Androgen-insensitivity syndromes in 46,XY fetuses result in various degrees of impairment in genital virilization.1 These syndromes are caused by mutations in the androgen receptor gene that result ...