Researchers from the Kops group in collaboration with researchers from the University of Edinburgh, made a surprising new discovery in the structure of the centromere, a structure that is involved in ...

Researchers have made a surprising new discovery in the structure of the centromere, a structure that is involved in ensuring that chromosomes are segregated properly when a cell divides. Mistakes in ...

Centromeres, specialized regions located at the center of chromosomes, are critical for ensuring proper cell division. During mitosis, centromeres serve as assembly sites for complex protein ...

Despite the immense amount of genetic material present in each cell, around 3 billion base pairs in humans, this material needs to be accurately divided in two and allocated in equal quantities. The ...

Despite the immense amount of genetic material present in each cell, around three billion base pairs in humans, this material needs to be accurately divided in two and allocated in equal quantities.

The Portuguese island of Madeira is home to six different chromosomal races of mice, each with dramatically reduced diploid chromosome numbers compared to mice elsewhere. This striking diversity, ...

Despite the immense amount of genetic material present in each cell, around three billion base pairs in humans, this material needs to be accurately divided in two and allocated in equal quantities.

Super-resolution microscopy image of a mitotic chromosome (white) with the centromeres of each sister chromatid depicted in orange. Each centromere consists of two distinct chromatin subdomains ...

In cells, CENP-A binds to histone H4 and HJURP before it is incorporated into the centromere. The previous model proposed that HJURP recognizes Mis18C and CENP-A is incorporated into the centromere ...