saw phagocytosis efficiency increase up to threefold. FIGURE 2: IgG3 antibodies are superior to IgG1 antibodies at inducing Fc-mediated phagocytosis ... More further potentiated when used as ...

The pandemic of coronavirus disease 2019 (COVID-19) has plagued the world for over a year now. In most cases, infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes ...

In a phase 2 trial, felzartamab showed acceptable safety and potential therapeutic benefits in kidney transplant recipients with antibody-mediated rejection. Felzartamab shows acceptable safety ...

and become internalized by macrophages during phagocytosis. Humoral immunity depends on lymphocytes to confer protection against infection through antibody-mediated functions, but it is not the only ...

The mechanism is believed to involve Fc receptor blockade, which prevents antibody-opsonized platelets from being destroyed by Fc receptor-mediated phagocytosis. It may also involve downregulation ...

Home » Antibody targeting of multiple P. aeruginosa evasion mechanisms enhances neutrophil-mediated phagocytosis and killing efficacy X Upgrade your daily dose of biopharma and medtech news ...

To better understand the mechanisms behind this antibody-mediated protection, researchers closely examined one particularly effective antibody targeting a molecule called lipoarabinomannan (LAM ...

More information: Evangelos Stefanidis et al, Combining SiRPα decoy–coengineered T cells and antibodies augments macrophage-mediated phagocytosis of tumor cells, Journal of Clinical ...