Researchers at the University of Bristol in the U.K. have applied an in silico method to model how carbapenems interact with bacterial beta-lactamase enzymes. The technique, reported this month in ...

Plasmid borne genes encoding modifying enzymes such as beta-lactamases, that confer resistance to penicillins and related antibiotics, or, more recently, phosphoethanolamine transferases, that confer ...

Among the more concerning findings in the report is that data from more than half of European countries show high resistance ...

that may inactivate certain beta-lactamase enzymes. Take with meals. Base dose on amoxicillin component. Due to clavulanic acid component: two 250mg tabs are not equivalent to one 500mg tab.

that may inactivate certain beta-lactamase enzymes. <3months: not recommended. Take with food. Base dose on amoxicillin component. Due to clavulanic acid component, ES-600 is not interchangable ...

Michael’s current work focuses on the screening, identification, and optimization of beta-lactamase inhibitory compounds, specifically those able to inhibit the hydrolytic enzyme KPC-2. Additional lab ...

A major challenge in AMR is carbapenem resistance, largely due to the enzyme New Delhi metallo-beta-lactamase (NDM), which renders bacteria resistant to carbapenem antibiotics—often the last ...

New Delhi metallo-beta-lactamase(NDM) driven carbapenem resistance is a major concern in hospitals across India, contributing significantly to the antimicrobial resistance burden. This enzyme ...