Three years ago, an NFL game between the Buffalo Bills and Cincinnati Bengals turned into a gut-retching moment when Bills safety Damar Hamlin suffered cardiac arrest and collapsed. Since then, Hamlin has made it his mission to increase awareness of CPR.

Steve Tasker and Thurman Thomas will be the Bills Legends of the Game for the final regular season game at Highmark Stadium on Sunday

Rhodes promoted the other KeyBank Center tenant. He held up a jersey of the Buffalo Bandits, who have won the last three National Lacrosse League championships.

Nichols School alumna Hayley Scamurra will represent Western New York playing for the U.S. women’s hockey team at the 2026 Olympic Winter Games. This will be the second Olympic trip for Scamurra, who was raised in Getzville and played college hockey for Northeastern,

The Buffalo Sabres' surprising nine-game win streak has been achieved by a revitalized defense, timely offense and veteran player performances.

Emotions filled an Erie County courtroom Friday when two teenagers were sentenced for the shooting death of a 3-year-old boy, Ramone "Lucky" Carter, also known as "Red."

Before he is officially sworn in as the next Mayor of Buffalo, Sean Ryan sat down with 2 On Your Side to talk about his administration, taxes and more.

A new year means a new name for Buffalo’s Children’s Hospital. Beginning Jan. 1, Oishei Children’s Hospital is now known as the Golisano Children’s Hospital of Buffalo. The name change is in recognition of a $50 million donation from Paychex founder and former Buffalo Sabres owner Tom Golisano.

Expert recap and game analysis of the Buffalo Bulls vs. Northern Illinois Huskies NCAAM game from December 31, 2025 on ESPN.