Medigene accelerates the expansion of its end-to-end platform of multiple, combinable, exclusive and proprietary technologies with the potential to create best-in-class T cell receptor engineered ...

CD28 is expressed on T cells providing costimulatory signals required for T cell activation and survival. Thus, the CD40L/CD40 pathway plays a crucial role in activation of T cells. Medigene´s ...

The key is a natural immune protein called CD40L. “We discovered that by adding CD40L to the immune cells in the lab, we could dramatically improve the number and quality of cancer-fighting T cells we ...

Gregory Sullivan, M.D., Chief Medical Officer of Tonix Pharmaceuticals said, “Topline results from the TNX-1500 Phase 1 study showed TNX-1500 at the 10 mg/kg and 30 mg/kg doses blocked both the ...

CD40L stimulates tumor-infiltrating B-cells and improves ex vivo TIL expansion. Journal for ImmunoTherapy of Cancer , 2025; 13 (4): e011066 DOI: 10.1136/jitc-2024-011066 Cite This Page : ...