Cadherin-17, also called liver-intestine cadherin, is a calcium-dependent transmembrane glycoprotein that mediates cell–cell adhesion in intestinal epithelium. Expression of cadherin-17 was reported ...

Cadherin-containing cell–cell junctions respond to intercellular tension by increasing their size, strength and complexity. The mechanical regulation of cadherin adhesions is now shown to involve ...

Researchers at the Johns Hopkins Kimmel Cancer Center discovered that a cell adhesion protein, E-cadherin, allows breast cancer cells to survive as they travel through the body and form new tumors, a ...

Researchers have comprehensively described the network of proteins involved in cell-cell adhesions, or the cadherin interactome. Many biological processes depend on the ability of cells to stick to ...

Fruit-fly ovaries were used in a new study to uncover how E-cadherin guides collective cell migration. According to traditional scientific dogma, E-cadherin acts like the mortar between bricks, ...

E-cadherin, a member of the cadherin family, has a very important role in organizing the epithelium. Most cancers arise from epithelial tissue, and in those cancers, cell adhesion mediated by ...

Breast cancer subtypes and outcome after local and regional relapse. Background: Triple-negative breast cancer (TNBC), which is characterized by negativity for ER, PR, and HER2, is a high risk breast ...

Randomized Trial of Adjuvant Chemotherapy With Mitomycin, Fluorouracil, and Cytosine Arabinoside Followed by Oral Fluorouracil in Serosa-Negative Gastric Cancer: Japan Clinical Oncology Group 9206–1 ...

Hindering Cadherin-22, a key cancer cell protein can help prevent the cancer cells from binding together and spreading, finds a new study published in Cell journal. The groundbreaking study identified ...

P-cadherin is a protein commonly found on malignant cancer cells and has been used as a target for antibody-based cancer treatments. UC Davis biomedical engineers have discovered that when an antibody ...

Researchers at The University of Texas MD Anderson Cancer Center have identified a targetable driver of brain metastases in ...

The paper A. Sing et al., “The atypical cadherin Fat directly regulates mitochondrial function and metabolic state,” Cell, 158:1293-1308, 2014. When clustered together in tissues, cells sense and ...