The finding that ER-to-mitochondria calcium flow is critical for multiple metabolic cancer pathways suggests that this mechanism could be an important target for future cancer therapies ...

The researchers examined the genomes of about 50,000 people to learn more about the association between CLDN14 and the metabolism of calcium ... attractive new pathway for drug discovery, and ...

In the signalling pathway that has now been discovered, calcium flows through the membrane channels into the cell and activates calcium-dependent enzymes that in turn activate the AMP-kinase. This ...

“It is our opinion that calcium with or without vitamin D modulates human energy metabolism ... the inclusion of mechanistic pathways in such investigations is essential in cementing the ...

The calcium sensing receptor (CaSR ... The present study revealed the protective role of CaSR in myocardial energy metabolism disorder induced by high glucose (HG) as well as the underlying ...

"We knew for years that calcium phosphate-based materials promote ... to her team that "the biomaterials were connected to metabolic pathways. And we didn't know how these metabolic pathways ...

Calcium plays an important part in bone metabolism and calcium supplementation ... that calcium may affect BMD through extracalcium pathways. Furthermore, dual-energy x-ray absorptiometry-derived ...

CaMKK2 is critical for a signaling pathway that regulates calcium and, as a result, essential brain functions like the formation of long-term memories, metabolic activities, behavior, and mood.

One of these pathways burns energy without transporting calcium, resulting in a futile cycle that wastes ... suggesting a GIPR-dependent metabolic memory. “[The results provide] a better understanding ...