Activities of papain-like cysteine proteases cathepsins B, C, F, H, K, L, S, V, X, papain and legumain were tested using the caspase substrates Ac-DEVD-AFC and Ac-WEHD-AMC (AFC=7-amido-4 ...

This pipeline outlays comprehensive information on the Caspase 3 (Apopain or Cysteine Protease CPP32 or Protein Yama or SREBP Cleavage Activity 1 or CASP3 or EC 3.4.22.56) targeted therapeutics ...

Caspase 8 (Apoptotic Cysteine Protease or Apoptotic Protease Mch 5 or CAP4 or FADD Homologous ICE/Ced-3 Like Protease or FADD Like ICE or ICE Like Apoptotic Protease 5 or MORT1 Associated Ced 3 ...

and MERS-CoV exploit a host protease called 'cysteine-aspartic protease 6' (caspase-6) for efficient replication. Researchers from Department of Microbiology, School of Clinical Medicine ...

Prior to this study, scientists believed that proteases primarily cleave in unstructured loops, unstable parts of proteins that are readily accessible. The discovery that caspase-3 also cleaves α ...

Activation and execution of apoptosis at molecular level are regulated by a family of cysteine proteases or caspases ... of consecutive reactions involving caspase activation, so-called caspase ...

Apoptosis is executed by cysteine-aspartic protease in human and animal cells, by which infected cells are eradicated to inhibit virus replication. The HKUMed team investigated the impact of caspase-6 ...

They published their findings in a Science article titled, “Craspase is a CRISPR RNA-guided, RNA-activated protease.” A recent finding that a caspase-like protein associated with CRISPR-Cas ...

Reporting in the September 9 Nature Chemical Biology, senior author Matthew Bogyo and colleagues demonstrate how the probes light up papain-family cysteine proteases in live mice. The fluorescent ...

and MERS-CoV exploit a host protease called ‘cysteine-aspartic protease 6’ (caspase-6) for efficient replication. The findings are peer reviewed and recently accepted for publication in the ...