Activities of papain-like cysteine proteases cathepsins B, C, F, H, K, L, S, V, X, papain and legumain were tested using the caspase substrates Ac-DEVD-AFC and Ac-WEHD-AMC (AFC=7-amido-4 ...

This pipeline outlays comprehensive information on the Caspase 3 (Apopain or Cysteine Protease CPP32 or Protein Yama or SREBP Cleavage Activity 1 or CASP3 or EC 3.4.22.56) targeted therapeutics ...

and MERS-CoV exploit a host protease called 'cysteine-aspartic protease 6' (caspase-6) for efficient replication. Researchers from Department of Microbiology, School of Clinical Medicine ...

Prior to this study, scientists believed that proteases primarily cleave in unstructured loops, unstable parts of proteins that are readily accessible. The discovery that caspase-3 also cleaves α ...

Activation and execution of apoptosis at molecular level are regulated by a family of cysteine proteases or caspases ... of consecutive reactions involving caspase activation, so-called caspase ...

Apoptosis is executed by cysteine-aspartic protease in human and animal cells, by which infected cells are eradicated to inhibit virus replication. The HKUMed team investigated the impact of caspase-6 ...

Reporting in the September 9 Nature Chemical Biology, senior author Matthew Bogyo and colleagues demonstrate how the probes light up papain-family cysteine proteases in live mice. The fluorescent ...

Caspases are a family of proteases that control programmed cell death in animals, including humans. A recent finding that caspase-like proteins could associate with CRISPR-Cas electrified the ...

and MERS-CoV exploit a host protease called ‘cysteine-aspartic protease 6’ (caspase-6) for efficient replication. The findings are peer reviewed and recently accepted for publication in the ...