STING (stimulator of interferon genes) is a key mediator of innate immunity and the STING pathway has been shown to be involved in the induction of an anti-tumor immune response. We recently spoke to ...

This paradigm shift from conventional treatments offers a more precise method to neutralize cancer cells. The cGAS-STING signaling pathway, a key element of the innate immune response, has risen ...

A key finding about the immune system's response to tumor development has been reported by researchers following studies on colorectal cancer ... genes (STING) signaling pathway may play an ...

"There's been millions of dollars invested in drugs that activate the STING pathway to fight cancer, and so far in clinical trials, they have not shown significant anti-cancer efficacy," Dr ...

It’s like the first ringing of the alarm bell for the immune system.” In cancer immunotherapy, the STING pathway is a well-known critical activator of cancer-killing T cells that kicks off the ...

Its central role in immunosurveillance positions the cGAS-STING pathway as an attractive anti-cancer immunotherapeutic drug target for chemical agonists or vaccine adjuvants and suggests a key ...

Researchers at Memorial Sloan Kettering Cancer Center have discovered that the STING cellular signaling pathway plays a key role in preventing dormant cancer cells from progressing into aggressive ...

The cGAS-STING pathway facilitates crosstalk between cancer cells and the tumor microenvironment (TME). The activation of cGAS-STING promotes the release and presentation of cancer antigens ...