The new workflow was adapted from an enzymatic DNA tagging technology, DNA-TAG, previously developed in the Devaraj lab. In ...

A research group is the first in the world to succeed in constructing artificial cell nuclei by injecting purified DNA solution instead of sperm into living mouse eggs. Their findings are published in ...

Gene therapy holds the promise of preventing and curing disease by manipulating gene expression within a patient's cells. However, to be effective, the new gene must make it into a cell's nucleus. The ...

Researchers at the Francis Crick Institute and King's College London have discovered that how soft or rigid proteins are in certain regions can dictate how fast or slow they enter the nucleus.

From middle school biology we were always taught that the nucleus is the “control center” of the cell, similar to how the brain is the control center of our own bodies. At first glance this makes a ...

Genes in the nucleus of the host cell have now replaced their functions. Nowack: "These fundamental findings help us understand how an organelle evolves from a bacterium. Using this mechanism, it may ...

The artificial cell nucleus (right) constructed using the purified DNA was morphologically very similar to the natural cell nucleus derived from an egg (left). A team led by Professor Kazuo Yamagata ...