Multimorbidity (MM), the presence of two or more chronic conditions, is increasingly common in clinical practice. Recent ...

The dehydrogenase complexes serve as pivotal regulators in cellular metabolism, orchestrating key oxidative reactions within the tricarboxylic acid (TCA) cycle and beyond. These multi‐enzyme ...

Glycolysis is a central metabolic pathway by which cells obtain energy from sugar. Cancer cells in particular have long been thought to depend on the energy obtained through glycolysis, a phenomenon ...

There are "costs of life" that mechanical physics cannot calculate. A clear example is the energy required to keep specific biochemical processes active—such as those that make up photosynthesis, ...

Glycolysis is an important sugar degradation pathway that cancer cells in particular depend on. Scientists at the German Cancer Research Center (DKFZ) have now shown that liver cancer cells in mice ...

New microbiome data show that intestinal bacteria can generate clinically relevant alcohol levels, validating a rare syndrome ...

Plant cell cultures are an attractive alternative to cultivating whole plants for obtaining natural compounds, but many ...

In several disease conditions, including infections and cancers, innate immune activation and nutrient scarcity occur together. A study from St. Jude Children's Research Hospital, published in Cell, ...

MD Anderson studies reveal how cancer cells rewire metabolism to spread. A glucose–fructose mix promotes colorectal metastasis via cholesterol pathways, while fatty-acid oxidation driven by ACBP ...

The field of cancer research has increasingly focused on the metabolic underpinnings of tumorigenesis, recognizing how the reprogramming of cellular energy ...

A compound from ginger stops cancer cells from making fats and drains their energy, exposing a metabolic weakness in cancer cells.