The genetic material inside cells is organized into structures called chromosomes. The centromere is essential for the correct division of the chromosomes via interaction with spindle microtubules ...

If I asked you, dear reader, to come up with a shortlist of the most monumental scientific achievements of the last century, chances are the Human Genome Project (HGP) would appear somewhere on that ...

Osaka, Japan – The genetic material inside cells is organized into structures called chromosomes. The centromere is essential for the correct division of the chromosomes via interaction with spindle ...

The centromere of chromosomes plays a crucial role in cell division. Using the model plant Arabidopsis thaliana, an international team of researchers has investigated how two crucial proteins -- KNL2 ...

Centromeric nucleosomes contain a histone H3 variant called centromere protein A (CENP-A) that is required for kinetochore assembly and chromosome segregation. Two new studies, Jansen et al. (see p.

Centromeres are curious structures. These specially organized chromosomal regions are best known for their unique and critical role in cell division, in which they are well understood to serve as the ...

When people think of DNA, they usually think of genes, the parts that code for proteins and drive inherited traits. But there's a whole lot of DNA beyond genes that we are just starting to understand.

The two proteins KNL2 and CENP-C are crucial for the correct separation of chromosomes during cell division. To dock to the centromere, the newly described additional binding regions (DNA-b) to the ...

Intriguingly, centromeric regions were also enriched in young long terminal repeat (LTR) retrotransposons, suggesting a potential role for transposable elements in shaping centromeric architecture and ...

We purified 15,000-fold from HeLa cell nuclear extract the centromere antigen that reacts specifically with the 17-bp sequence, designated previously as CENP-B box, in human centromeric α-satellite ...