Identification of pSTAT5 gene signature in hematologic malignancy. This is an ASCO Meeting Abstract from the 2013 ASCO Annual Meeting I. This abstract does not include a full text component.

Common genetic variants affect the risk of abnormalities in chromosome number (a phenomenon known as aneuploidy), a major cause of pregnancy loss, according to a study published in Nature. The ...

Stefan Fröhling, M.D., and Hartmut Döhner, M.D. The cause of chromosomal abnormalities remains poorly understood. Studies of various types of leukemia have shown that certain environmental and ...

I still recall my disappointment one day in 2015. I received the tumor DNA sequencing results for one of my patients, whose cancer had spread from her lungs to her brain. I saw not a single genetic ...

The improper segregation of chromosomes during cell division leads to abnormalities that disrupt the proper functioning of the cell. Cells with an abnormal number of chromosomes consequently activate ...

Translocations, in genetics, happen when chromosomes break and the pieces attach to other chromosomes. This mixing of genetic material has important results. The resultant chromosomes are lacking in ...