Find patient medical information for Cisplatin on WebMD including its uses, side effects and safety, interactions, pictures, warnings, and user ratings ...

Cisplatin forms intrastrand cross-links on DNA and is a widely used chemotherapy agent. Among human translesion DNA polymerases, Pol-η can bypass cisplatin adducts. The crystal structure of human ...

Cisplatin is known to have an additive or synergistic effect in combination with gemcitabine in a number of different tumor types (e.g., lung, 9 bladder, 10 and head and neck 11 cancers).

Many patients who can't tolerate cisplatin are of an advanced age and/or have other health issues, he noted. More information. There's more on head-and-neck cancers at the American Cancer Society.