New research from the University of California, Irvine, finds that drug withdrawal-induced anxiety and reinstatement of drug seeking behaviors are controlled by a single pathway in the brain and ...

White matter in the brain that was previously implicated in animal studies has now been suggested to be specifically impaired in the brains of people with addiction to cocaine or heroin, according to ...

Long-term abuse of cocaine induces compensatory changes in numerous genes associated with brain function. These compensatory changes lead to the appearance of the classic series of withdrawal symptoms ...

New research from the University of California, Irvine, finds that drug withdrawal-induced anxiety and reinstatement of drug seeking behaviors are controlled by a single pathway in the brain and ...

Study: Molecular and circuit determinants in the globus pallidus mediating control of cocaine-induced behavioral plasticity. Image Credit: Alex Mit / Shutterstock.com Ventral tegmental area dopamine ...

Brain-derived neurotrophic factor (BDNF) and its precursor, proBDNF, are known to significantly contribute to brain homeostasis, neuroplasticity, and neuronal remodeling. Although these neurotrophins ...

Cocaine/crack abstinence periods have higher risk of relapse. Abstinence as initial part of the recovery process is affected by learning and memory changes that could preserve the addictive cycle. To ...

Cocaine is a stimulant drug and highly addictive. Using cocaine can cause changes to the brain, such as in the reward system, resulting in a buildup of dopamine and making it difficult for someone to ...

New research finds that drug withdrawal-induced anxiety and reinstatement of drug seeking behaviors are controlled by a single pathway in the brain and centered around dopamine cells. New research ...