Researchers used epigenome engineering and CRISPR to reprogram sperm DNA, allowing embryos to develop with only fathers.

Moving toward clinical development, the researchers demonstrated efficient delivery of mRNA mitochondrial base editors using ...

Males imprint their DNA by adding methyl modifications to it in a way that alters the activity of genes in order to promote ...

CRISPR-Cas tools allow researchers to modify individual building blocks of genetic material in a precise and targeted manner. Gene therapies based on such gene editing are already being used to ...

To carry out the experiment, researchers used sperm from two different strains of mice. One strain was bred in European labs; ...

RNA gene scissors (CRISPR-Cas13) are gaining significant attention as a next-generation gene therapy with fewer side effects. They can suppress infection by eliminating viral RNA, such as in ...

But CRISPR-Cas now appears to go even further than cutting DNA. “When we discovered CRISPR-Cas, we observed that it cuts viral DNA in precise locations,” explains Brouns.

CRISPR-Cas systems help to protect bacteria from viruses. Several different types of CRISPR-Cas defense systems are found in bacteria, which differ in their composition and functions. Among them ...

More information: Edgardo Santiago‐Rivera et al, Spider Eye Development Editing and Silk Fiber Engineering Using CRISPR‐Cas, Angewandte Chemie International Edition (2025). DOI: 10.1002/anie ...

CRISPR-Cas tools allow researchers to modify individual building blocks of genetic material in a precise and targeted manner. Gene therapies based on such gene editing are already being used to treat ...