In yeast, the CDK and cyclin proteins that drive cell division activate first in the nucleus — a different location in the cell from where was previously thought. James E. Ferrell Jr is in the ...

Gene therapy holds the promise of preventing and curing disease by manipulating gene expression within a patient's cells. However, to be effective, the new gene must make it into a cell’s nucleus. The ...

Over the past decade, there have been scattered reports of mammalian cells’ own DNA being found in the cytoplasm, mainly in the context of disease and aging. While it is not unusual to find DNA from ...