DNA methylation profiles in whole blood samples from 77 patients with CN-AML in The Cancer Genome Atlas (LAML cohort) were analyzed. Individual 5’-cytosine-phosphate-guanine-3’ (CpG) sites were ...

Polβ-dependent DNA demethylation is essential for neuronal development. During neuronal development, DNA demethylation at enhancer regions is required to activate gene expression. In the absence of ...

A new study by scientists at deCODE Genetics, a subsidiary of Amgen, shows that sequence variants drive the correlation between DNA methylation and gene expression. The same variants are linked to ...

*Important notice: bioRxiv publishes preliminary scientific reports that are not peer-reviewed and, therefore, should not be regarded as conclusive, guide clinical practice/health-related behavior, or ...

A new study draws a line between random genetic mutations and predictable epigenetic changes used to measure biological aging. When you purchase through links on our site, we may earn an affiliate ...

Development of a comprehensive cfDNA methylation signature for prognostic, predictive, and diagnostic applications in pancreatic ductal adenocarcinoma (PDA). This is an ASCO Meeting Abstract from the ...