Pharmacodynamic interactions alter pharmacologic efficacy of a drug, although drug plasma levels remain unaltered. 2 This has an impact on either the pharmacologic efficacy or on the magnitude of side ...

A recent US Food and Drug Administration (FDA) advisory committee meeting highlighted the potential of clinical pharmacology to overcome challenges in orphan drug development. There has been marked ...

Needing to frequently adjust drug dosages in patients who are prescribed multiple medications could point to drug-drug interactions that had not been previously known, suggest study findings published ...

Clinical pharmacologists have achieved major progress for improving the reliability of drugs. In a pharmacological study, they showed that interactions between drugs can be detected with minute doses ...

Within the International Union of Pharmacology (IUPHAR), several answers to the question “What is pharmacology?” have been given 1. The subject of pharmacology has been given various definitions in ...

For more than 20 years, the University of Washington has been home to a database built, maintained and expanded around the goal of helping to prevent health complications from adverse drug reactions, ...

Regulators, developers, and testing laboratories are exploring in silico models, transporter assays, and other options to better predict drug combination outcomes In the future, many drug–drug ...

Drugs absorbed into the body are metabolized and thus removed by enzymes from several organs like the liver. The how fast the drug is cleared out of the system can be increased by other drugs that ...

We live in a world where drugs exist to treat many conditions that seemed untouchable in the past. In a report that looked at U.S. prescription drug use from 2015 to 2018, the Centers for Disease ...

All software under review was downloaded from the manufacturers' Web sites from December 2002 to July 2003. The following software was evaluated: ePocrates Rx (v. 6.0), Tarascon PharmacopoeiaDeluxe ...