Pathological features in Alzheimer’s brains include mitochondrial dysfunction and dystrophic neurites (DNs) in areas surrounding amyloid plaques. Using a mouse model that overexpresses reticulon 3 ...
Cells use signaling networks to carry out their functions, and new work has shown how stress can reshape those networks. The research reveals novel mechanisms that relay messages to cellular machinery ...
A recently paper published in Cell reports that dendritic cells (DCs) are dysfunctional in the tumor environment. Tumor impairs DC function through induction of endoplasmic reticulum stress response ...
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