Tuberculosis is the world's leading infectious cause of death, killing more than one million people each year. When the ...

Zhiqi Xiong et al, Structure and assembly of the MmpL5/MmpS5 efflux transporter from Mycobacterium tuberculosis, Nature Communications (2025). DOI: 10.1038/s41467-025-60365-5 ...

Scientists at the University of Cambridge have uncovered the final piece in the jigsaw revealing the structure of ‘efflux pumps’, which allow Salmonella and other disease-causing bacteria to develop ...

Efflux Pump’s Shape Shifting Sheds Light on Antibiotic Resistance February 18, 2022 MIT chemists have discovered how the structure of the EmrE transporter changes as a compound moves through it.

Efflux pumps represent one mechanism by which S. aureus has evolved resistance to fluoroquinolones, ... which enhanced the cryo-EM images and revealed the NorA pump's structure for the first time.

Efflux pumps represent one mechanism by which S. aureus has evolved resistance to fluoroquinolones, ... which enhanced the cryo-EM images and revealed the NorA pump’s structure for the first time.

Spatial Characteristics of the Efflux Pump MexB Determine Inhibitor Binding. Antimicrobial Agents and Chemotherapy , 2022; DOI: 10.1128/aac.00672-22 Cite This Page : ...

image: The inhibitor-binding site of the wild-type MexB pump. (a) The crystal structure of the inhibitor ABI-PP bound to the MexB trimer. Three MexB monomers are shown in green, blue, and red ...