In higher eukaryotes, a vast variety of RNAs is transcribed from genomic DNAs. The transcribed RNAs are subjected to RNA processing steps, such as splicing, ...

How does a gene ... prokaryotic regulation delve into each of these topics, leading to primary literature in many cases. For eukaryotes, cell-cell differences are determined by expression of ...

coli? The answer lies in the difference in gene expression and regulation used. Regulation of transcription in eukaryotes is a result of the combined effects of structural properties (how DNA is ...

Our research program focuses on two primary points of control: transcription of messenger RNA (mRNA) and post-transcriptional regulation of mRNAs by microRNAs (miRNAs). A critical control point for ...

Recent technological advances are fueling the development of cutting-edge technologies that can monitor and control ...

Autism spectrum disorder (ASD) is a condition affecting the brain's development and often affects the ability of a person to ...

An elegant screening strategy unveils a molecular actor that connects widespread changes in mRNA processing with a nutrient-sensing protein modification.

Constitutive splicing is where every intron in the primary RNA transcript is removed as transcription progresses along the gene. Alternative splicing is where exon or intron skipping can occur.

“There isn’t one mode of microRNA regulation: There are two.” This isn’t the first time that miRNAs were found to enhance gene expression. A paper published in Science in 2007 pointed to cases of ...

A study published today in the journal Cell marks the first reported instance of generative AI designing synthetic molecules that can successfully control gene expression in healthy mammalian cells.

“It could just be some sort of up-regulation that's associated with having high metabolisms or just being a shrew in general.” Furthermore, since hypothalamic gene expression responds to environmental ...