Google's DeepMind launches AlphaGenome, an artificial intelligence model that predicts gene expression from DNA sequence.

Contrary to earlier predictions, their research showed that Set8 controls gene activity and cell proliferation via a mechanism other than chemically modifying the histone protein.

Scientists identified 473 human genes that act as genetic “on/off switches,” shaping disease risk through tissue-specific or ...

Chromatin modifications are thought to contribute to the regulation of key biological processes such as development, response to environmental signals, and disease. To understand the effects of ...

Gene regulation in multicellular eukaryotes is complex, with many layers of regulation. Two fundamental mechanisms of gene regulation involve transcription factors and microRNAs, a large class of ...

Controlling gene expression is essential to growth, development, and sustained life. This requires regulating the spacial, temporal, and developmental expression of genes in a wide diversity of cell ...

Reference: Pramio DT, Vieceli FM, Varella-Branco E, et al. DNA methylation of the promoter region at the CREB1 binding site is a mechanism for the epigenetic regulation of brain-specific PKMζ. Biochim ...

Epigenome Editing Toolkit Elucidates Gene Regulation Mechanisms. May 9, 2024. A molecular model showing three of the main epigenetic modifications of DNA (orange) and histones ...

Life X DNA™, an Australian-based provider of genetic analysis services, offers DNA methylation testing designed to help individuals better understand biological processes that may influence health.

This complex mechanism is mainly driven by the interaction between proteins called transcription factors, ... To understand the effects of specific chromatin marks on gene regulation, ...

Epigenetic regulation is a key mechanism in the fibrogenic activation of HSCs, influencing gene activity without altering the ...

The study of gene regulation — how genes come to be expressed and how gene expression can be controlled — is an important area of research at Fred Hutch and is foundational to the design of many ...