A protein that's essential to every cell's ability to turn off unnecessary genes is well known for its key function of ...

Understanding gene regulation may be key to interpreting human disease genetics. Genes are regulated in part by stretches of DNA called enhancers, which define when, where and how strongly each gene ...

An international team of researchers has assembled one of the largest single-cell genetic atlases ever built, profiling more ...

Some sequences in the genome cause genes to be switched on or off. Until now, each of these gene switches, or so-called enhancers, was thought to have its own place on the DNA. Different enhancers are ...

Genetic disorders — like cystic fibrosis and Huntington’s disease — are considered incurable, with gene mutations occurring in essentially every cell of the body. Gene mutations occur when one ...

Understanding human biology requires more than mapping our genes – we must also understand how gene expression is regulated to guide healthy development, growth, and maintenance of our body systems ...

Variants in genes involved in the production of extracellular matrix molecules could have enabled the skeletal adaptations that distinguish humans from other great apes.

An estimated 170,000 Australians were diagnosed with cancer in 2025. Many people know the causes of cancer are partly genetic. But how do your genes, which contribute so much of what makes you you, ...

Autism spectrum disorder (ASD) is associated with more than 1,200 risk genes, raising a fundamental question: Do these diverse genetic changes affect the brain in entirely different ways, or do they ...

Researchers analyzed gene expression across 17 autism-linked mouse lines and found two opposing molecular states, suggesting diverse risk mutations can converge on shared brain biology.