Mutation rates govern the introduction of genetic variation and influence evolutionary trajectories, disease susceptibility and species diversity. Rates are shaped by a balance between DNA damage, ...

C EGFR T790M gene variant face roughly 25 times the lung cancer risk of noncarriers, according to the largest-yet study of ...

Finding a place for "chance" in evolutionWhen we encounter the forms and mechanisms of living things, we ask, "What is the use of this?" Bird wings are useful for flying, and fish gills are useful for ...

How do bacteria adapt when resources run low? ISTA researchers have found that, under starvation stress, E. coli can use ...

A new study by scientists at City of Hope and TGen, part of City of Hope, found surprisingly large differences in the number of mutations present in the organs of healthy individuals. Some study ...

A new study of 450 colorectal cancer patients has delivered some of the clearest evidence yet that mutations in two DNA proofreading genes, POLE and POLD1, can identify which patients are most likely ...

In simple terms: a mutation is a stable change in genetic sequence that can be copied when cells or viruses replicate. Most mutations have no detectable effect, some contribute to disease, and a small ...

Most lethal mutations in wild fruit flies are driven by newly transferred jumping genes, not small DNA errors, according to a new study from Duke University. The findings, published in PLOS Biology, ...

The short legs of a Dachshund. The folded ears of a Scottish Fold.Both are traits that have become reasons for choosing these ...

Smoking is one of the biggest contributors to lung cancer, but anywhere from 10-20% of cases in the U.S. each year are diagnosed in people who never smoked. In a new study published in Science, ...

Bladder cancer remains one of the most common and deadly malignancies worldwide, and researchers continue to hunt for ...