A therapy originally developed for HIV now provides new options for patients with rare genetic disorders. It’s now possible to use these drugs to address DNA defects and enhance muscle function. This ...

Macquarie University researchers have discovered a naturally occurring protein found in human cells plays a powerful role in repairing damaged DNA—the molecule that carries the genetic instructions ...

A cancer drug target already being investigated in clinical trials turns out to be doing something even more consequential ...

For decades, the dream of fixing harmful mutations in mitochondrial DNA felt out of reach. Scientists have long known these mutations cause serious diseases that pass down only through mothers. They ...

Mitochondria are often described as the cell’s power plants, but a wave of new research suggests their genetic material may also hide a critical, underappreciated source of disease. Scientists are ...

Researchers shed new light on G-quadruplexes, a type of secondary DNA structure that has attracted attention as a potential therapeutic target in cancer. Every day, billions of cells in your body ...

A research team led by Eske Willerslev, professor at the University of Copenhagen and the University of Cambridge, has recovered ancient DNA from 214 known human pathogens in prehistoric humans from ...