Hepatocellular carcinoma (HCC) is a leading cause of cancer-related death globally, with incidence continuing to rise in many regions. Despite advances in ...

Charles Gersbach and his colleagues are pursuing promising CRISPR technologies focused on controlling gene activity rather ...

Genome editing is revolutionizing the medical landscape by offering new therapeutic possibilities for genetic diseases, which collectively affect hundreds ...

The last time The Lancet Microbe featured an Editorial on CRISPR was in November 2020, to mark that year’s Nobel Prize in Chemistry, jointly awarded to Emmanuelle Charpentier and Jennifer A Doudna for ...

The gene editing treatment targets the relatively common 1717-1G>A splicing mutation, which does not respond to many current CF therapies.

Scientists have unveiled two major CRISPR breakthroughs: a ThermoCas9 variant that can distinguish and cut tumor DNA while sparing healthy cells, and a retron-based editing system adapted from E. coli ...

A platform approach to gene editing brings together design, manufacturing, validation, analytics, and regulatory considerations right from the start.

The rapid evolution of CRISPR/Cas genome editing has redefined the possibilities of cellular and gene therapy, enabling ...

The publication, titled “ Comparative characterization of Cas12f orthologs reveals mechanistic features underlying enhanced genome editing efficiency” highlights the potential of MG119-28 (formally ...

Artificial intelligence is accelerating advances across genetics, from precision genome editing to complete crop genome mapping and personalized disease risk prediction. Recent achievements include ...

The Pairwise Fulcrum® platform includes proprietary gene editing tools, enzymes, and trait libraries that enable precise genetic changes, unlocking plants’ inherent potential and significantly ...