How does germ cell development in mice work ... functional gametes that make it possible for the cycle of life to perpetuate generations of animal species. But the most difficult questions ...

After a flurry of cell divisions from the starting “germ cell” (i.e. united egg and sperm), somatic cells begin to exit the cell cycle as the DREAM complex suppresses the proliferative germ cell ...

In each cell cycle, the integrity of genetic and epigenetic ... early mammalian embryonic development and during primordial germ cell (PGC) development highlights the intrinsic reversibility ...