Recent investigations, to which the author has made valuable contributions, tend to show that the distinction, once established, is irrevocable, and that germ-cells are derived from pre-existing ...

Germ cell genotype controls cell cycle during spermatogenesis in the rat. Biol Reprod 1998; 59: 1371–1377. Article CAS Google Scholar Spiller C, Wilhelm D, Koopman P . Cell cycle analysis of ...

Primordial germ cells, which emerge around day 16 in early human embryos, develop to form oogonia so that eventually, the number of oocytes that are present in an adult female is fixed at birth.

Germ cell tumors aren’t always cancer, but they can be. Learn what causes them, what to look for, and how they’re treated.

PGCs did not, however, express genes known to be turned on later in the process of germ cell development, when precursor cells migrate to the ovaries or testes to complete their maturation.

Expanding homogeneous culture of human primordial germ cell-like cells maintaining germline features without serum or feeder layers. Stem Cell Reports, 2022; DOI: 10.1016/j.stemcr.2022.01.012; ...

From the somatic cell to the germ cell Date: June 8, 2017 Source: Albert-Ludwigs-Universität Freiburg Summary: A regulatory pathway that changes the way cells divide in plants has been discovered ...

A review of the state of the art in managing germ cell tumors (GCTs) in 2018 differs from that of virtually all other malignancies in which novel therapies releasing checkpoints in the immune system ...

“In humans, failure to migrate to the ovary or testes can compromise fertility and lead to the formation of germ cell tumors.” But how do primordial germ cells reach their target? Barton, a ...

In the new studies, UC Davis postdoctoral fellow Yuka Kitamura identified two proteins in germ cells that establish this cellular memory. The first, called SCML2, disconnects junctions and allows the ...