Primordial germ cells, the founder cells of the germ line, are set aside in the early animal embryo, and divide and differentiate to produce sperm and egg, the male and female gametes. CLDN11 is ...

This review focuses on intergenerational and transgenerational epigenetic inheritance in different plants, animal species and humans, presenting the up-to-date evidence and arguments for such effects ...

Mutations can be grouped into two main categories based on where they occur: somatic mutations and germ-line mutations. Somatic mutations take place in non-reproductive cells. Many kinds of ...

Two weeks after a human egg is fertilized, primordial germ cells (PGCs), which develop into sperm and eggs, are formed. In six to 10 weeks after fertilization, PGCs differentiate into pro ...

Where the law takes issue however, are any changes to “germ line” cells — those that could pass on edits to a future human. Namely, eggs or sperm. Recently, Canadian researchers, working ...

The nucleus of a germline stem cell undergoes two divisions, firstly separating homologous chromosomes and secondly separating chromatids. Haploid gametes contain 23 single chromosomes.

Gene therapy is used to treat large number of diseases. Research in the field of human gene therapy is directed towards correcting genetic defects of somatic cells i.e., cells that do not ...