"It's known that germline structural variation also can contribute to the molecular profile of cancers," Creighton said. "Here we study the extent of its contribution." The researchers worked with ...

“And starting off by saying we should have a moratorium brings an important clarity to the thing.” Editing heritable DNA, or germline editing, involves using CRISPR-Cas9 or other methods to tweak the ...

TD Cowen reinstated coverage on Tempus AI with a "Buy" rating and raised its price target to $74 after the health-tech ...

The PubMed database was searched from January 2018 to May 2024. Articles were selected for inclusion if they reported on patients with metastatic prostate cancer who received a germline or somatic ...

constructed using gene segments from antibodies of different germline origins. Figure 2: Top view of the scFv antibody fragments specific for fluorescein isothiocyanate (FITC; clone FITC8), MUC1 ...

Risk of proteinuria with atezolizumab plus bevacizumab versus lenvatinib in first-line systemic treatment for hepatocellular carcinoma. End-of-life (EOL) outcomes and healthcare utilization for ...

The guideline authors used data from 61 studies to provide recommendations on the use of neoadjuvant chemotherapy in patients with newly diagnosed, stage III-IV epithelial ovarian, fallopian tube, or ...

Their study showed that DCIS patients with pathogenic variants in BRCA1/2 and PALB2 had a higher risk of developing invasive breast cancer than those without.

The nucleus of a germline stem cell undergoes two divisions, firstly separating homologous chromosomes and secondly separating chromatids. Haploid gametes contain 23 single chromosomes.