Lower estimated tubular secretion was found to be associated with a faster decline of estimated glomerular filtration rate (eGFR) but wasn’t associated with progression of chronic kidney disease or ...

Drugs are eliminated in the kidney by glomerular filtration and/or tubular secretion. Uptake transporters in the basolateral membrane and export transporters in the luminal membrane of renal tubule ...

Renal drug excretion involves filtration, reabsorption, and secretion, crucial for drug clearance and minimizing toxicity. The study models renal clearance using pharmacokinetic parameters, validated ...

The glomerular filtration rate (GFR) assesses the function of all nephrons, and the single-nephron GFR assesses the function of individual nephrons. How the single-nephron GFR relates to demographic ...

The glomerular filtration rate (GFR) is a measure of how well your kidneys are removing waste from your blood, which can be determined using an estimated GFR (eGFR) test. The test gets its name from ...

A GFR of over 90 is considered normal. But having a GFR of 60 or above may also be considered within the normal range if you do not have other signs of kidney disease. Diabetes is a long-term (chronic ...

Proteinuria is a defining feature of focal segmental glomerulosclerosis, typically accompanied by hypoalbuminemia, hypercholesterolemia, and peripheral edema. The nephrotic syndrome in children is ...

Please provide your email address to receive an email when new articles are posted on . Semaglutide positively affected renal fat mass, glomerular hemodynamics, inflammation and cortical fibrosis.