NextCure is joining the China biopharma gold rush, partnering with Simcere Pharmaceutical Group on development of a novel ...

A Roots Analysis study showed the market for ADC manufacturing is $1.79 billion today, but is expected to grow to $7 billion ...

[74] First, a gold electrode was modified with AuNPs and a thiolated capture probe was immobilized onto the electrode via sulfur–gold affinity. Then, a linker DNA containing an antiadenosine ...

High performance fluorescently conjugated antibodies designed for flow cytometry and beyond help researchers improve data reliability and streamline experimental design. As for many antibody-based ...

Scientists have turned to antibodies, and their natural targeting affinity, as a potential solution. Antibody-drug conjugates (ADC) combine the tumor-targeting potential of antibodies with the potency ...

Sanofi has developed a simpler way to create site-specific antibody-to-mannose-6-phosphate (M6P) conjugates that eliminates the need for enzyme remodeling. This more straightforward method makes ...

Assessing the pharmacokinetics (PK) of antibody-drug conjugates (ADCs) in both preclinical and clinical settings is crucial for their development. Biotransformation processes can lead to the ...

Two pharma giants have struck up international licensing collaborations involving antibody–drug conjugates (ADCs). ADCs use their antibody component to guide a drug payload to specific sites in ...

The first-in-class antibody-drug conjugate (ADC) pivekimab sunirine (PVEK) demonstrated promising efficacy and high response ...

ZW191 is a novel drug called a folate receptor-alpha (FRα) targeted topoisomerase I inhibitor antibody-drug conjugate, according to a news release from Zymeworks, the drug’s manufacturer. An ...