In the sofosbuvir–velpatasvir group, 34% of the patients had HCV genotype 1a, 19% genotype 1b, 17% genotype 2, 19% genotype 4, 6% genotype 5, and 7% genotype 6. Most patients were white (79% ...

(HealthDay News) — A new regimen shows promise for hepatitis C virus (HCV) genotype 1 infection ... and among those with 1a infection (97.0 and 90.2%, respectively). Stefan Zeuzem, MD, from ...

Cure rates were lower, however, for genotype 1a patients with liver cirrhosis. People with HIV and hepatitis C virus (HCV) co-infection experience more rapid liver disease progression than people with ...

Patients were excluded if they had coinfection with human immunodeficiency virus or hepatitis B virus or if they had infection with any HCV genotype other than 1a (PEARL-IV study) or 1b (PEARL-III ...

Each hepatitis C genotype has a different genetic makeup that helps define it. There are six basic genotypes. Scientists break down each of these numbers into subtypes by letters, like 1a ...

The most common HCV genotypes in the United States include: genotype 1 genotype 2 genotype 3 This further classifies into 1a and 1b, and 2a, 2b, and 2c. Of these subtypes, 1a, 1b, 2, and 3 are ...

The new drug combination showed an advantage in three of a total of 16 patient groups, particularly regarding virologic response. The extent of added benefit remains unclear, however. The fixed ...

According to the findings, there are indications of an added benefit in patients who have not yet developed cirrhosis of the liver and who are infected with the hepatitis C virus (HCV) genotype 1a ...

In hepatitis C, refers to undetectable hepatitis C RNA after treatment ... All but one relapse occurred amongst people with genotype 1a. Most of these patients who underwent resistance testing (79%) ...

Of the 75 patients who had virologic breakthrough during the trial, 50 had HCV genotype 1a infection. Relapse occurred in 19% of those in the TID16W group, 2% of those in the TID28W group ...

[hmicms_related_articles] Viekira XR, approved in 2016, is indicated for the treatment of chronic HCV genotype 1a (in combination with ribavirin) or 1b infection without cirrhosis or with ...

The drug dasabuvir (trade name Exviera) has been available since January 2015 for the treatment of adults with chronic hepatitis C infection. The German Institute for Quality and Efficiency in ...