Activated CD4 + T helper cells interact with dendritic cells ... reflect the kinetics of cargo production and the distinct organelles used for trafficking. Confocal imaging of fixed CTL–target ...

They found that T RM cell formation depends on processes in cellular organelles called mitochondria. Additionally, signaling ...

Identifying this organelle as a potential target to improve the performance of T-cells in the TME, the team set out to investigate the stress response of the Golgi to this environment and identify ...

They found that a specific type of immune cell, called T follicular helper cells, indirectly controls the anti-influenza response. These helper cells often "see" the wrong parts of the virus ...

Biol. 2021, DOI: 10.1038/s41589-021-00840-4). Researchers have made such synthetic organelles before, but they haven’t used them to program cell function. That the researchers could turn cell ...

The Yoko Hamazaki Laboratory at CiRA has reported that the slower onset of helper T-cell responses in the elderly after COVID-19 vaccinations is associated with lower antibody production ...

A key player in the immune response is T follicular helper cells. These Tfh cells are essential in vaccination responses, but they can be harmful actors in an autoimmune disease like lupus. Now, a ...

Picture a living cell as if it were a city. If you were the urban planner for this (very little, very alive) city, one of the ...

Scientists at the Sloan Kettering Institute have discovered a new organelle. The finding challenges longstanding ideas about cell structure. Many people probably remember cell organelles from high ...

A key part of the immune system, T cells can recognize fragments of viruses. When the cells identify a viral protein, helper T cells release chemical signals that trigger other parts of the immune ...