Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, No. 29 (July 22, 2014), pp. 10654-10659 (6 pages) A majority of mitochondrial DNA (mtDNA) mutations reported ...

Investigators led by a team at Massachusetts General Hospital (MGH) have made discoveries at the single cell level to uncover new details concerning mitochondrial diseases—inherited disorders that ...

Researchers have succeeded in creating embryos with 'heteroplasmy,' or the presence of both maternal and paternal mitochondrial DNA. This new innovation will allow scientists to study treatments for ...

Mitochondrial diseases are a heterogeneous group of disorders with varying clinical features caused by impaired function of the mitochondrial respiratory chain. The underlying cause can be gene ...

Mitochondrial diseases affect approximately 1 in 5,000 people worldwide, causing debilitating symptoms ranging from muscle weakness to stroke-like episodes. Some of these conditions result from ...

Mitochondrial diseases affect approximately 1 in 5,000 people worldwide, causing debilitating symptoms ranging from muscle weakness to stroke-like episodes. Some of these conditions result from ...

Pathogenic variants in mitochondrial DNA (mtDNA) are a common cause of severe, often fatal, inherited metabolic disease. A reproductive care pathway was implemented to provide women carrying ...

Mitochondrial donation through pronuclear transfer resulted in several live births and reduced transmission of pathogenic mitochondrial DNA (mtDNA) variants, researchers reported. The study involved ...

Investigators have made discoveries at the single cell level to uncover new details concerning mitochondrial diseases -- inherited disorders that interfere with energy production in the body and ...