Using the three cytokines to trigger IBD-like conditions, the researchers examined whether a similar treatment of a commonly used cell line used to model IBD could produce a comparable response ...

Preclinical models are simplified tools that help researchers study these complex interactions in a controlled manner and prioritize relevant biochemical pathways when developing IBD therapies ...

A research team from the Medical University of Vienna has made further progress in the treatment of intestinal inflammation.

In the guts of patients with inflammatory bowel disease (IBD), adenosine triphosphate (ATP) produced outside of cells leads to intestinal inflammation. Francisco Quintana, an immunologist and ...

BERLIN — Gut microbial biomarkers identified using machine learning can differentiate patients with inflammatory bowel disease (IBD ... using a machine learning model. The findings were tested ...

For patients with inflammatory bowel disease (IBD), risk factors associated with Clostridioides difficile infection (CDI) ...

Signaling proteins released by immune cells that promote inflammation. High levels of these molecules are associated with chronic inflammatory diseases, including IBD. Proteins that form connections ...

The mechanism underlying mucosal damage in IBD could involve a dysregulated, extreme T-cell response to normal enteric bacteria, and inhibition of this immune response could potentially be an ...