Using the three cytokines to trigger IBD-like conditions, the researchers examined whether a similar treatment of a commonly used cell line used to model IBD could produce a comparable response ...

The following is a summary of "AI-driven Personalized Medicine: Transforming Clinical Practice in Inflammatory Bowel Disease, ...

Preclinical models are simplified tools that help researchers study these complex interactions in a controlled manner and prioritize relevant biochemical pathways when developing IBD therapies ...

In the guts of patients with inflammatory bowel disease (IBD), adenosine triphosphate (ATP) produced outside of cells leads to intestinal inflammation. Francisco Quintana, an immunologist and ...

Background GPR171 suppresses T cell immune responses involved in antitumour immunity, while its role in inflammatory bowel disease (IBD) pathogenesis remains unclear. Objective We aimed to investigate ...

Inflammatory bowel disease (IBD) is impacted by genetic, environmental and immunological factors, where the imbalance in T-cell immune responses significantly promotes its progression. In recent years ...

Abdominal pain, diarrhea, weight loss—these and the other symptoms of inflammatory bowel disease (IBD ... adjusting the presence or absence of a model human gut microbiome and the dietary ...

Signaling proteins released by immune cells that promote inflammation. High levels of these molecules are associated with chronic inflammatory diseases, including IBD. Proteins that form connections ...

For patients with inflammatory bowel disease (IBD), risk factors associated with Clostridioides difficile infection (CDI) include recent diagnosis, corticosteroid usage, and hospitalization, according ...