The advancement in the field of immunotherapeutics has led to a new drive to comprehend the tumor microenvironment. Immunohistochemistry is a robust tool for the investigation of the expression, ...

The combination of digital pathology with immunohistochemistry is helping to resolve a major issue that has until now limited the accuracy and reliability of the immunohistochemical technique. In a ...

Immunohistochemistry (IHC) is a newer technique for assessing the estrogen receptor (ER) status of breast cancers, with the potential to overcome many of the shortcomings associated with the ...

To be adopted in the routine clinical setting, a biomarker must both demonstrate a clear additional benefit over standard clinical, radiological, and pathological examination (usually to predict ...

Immunohistochemistry plays a key role in the diagnosis of soft tissue tumors. Until recently, however, the primary purpose of immunohistochemistry in this context was simply to attempt to demonstrate ...

Immunohistochemistry (IHC) has continually evolved alongside technological and scientific advances. Because scientists constantly develop and modify their IHC techniques to better answer modern ...

A new study evaluates immunohistochemistry-based subtype classification of breast tumors for the prediction of disease outcome. A study by Paul Pharoah and colleagues published in this week's PLoS ...

High Expression of FGD3, a Putative Regulator of Cell Morphology and Motility, Is Prognostic of Favorable Outcome in Multiple Cancers We optimized and validated immunohistochemistry assays in breast ...

Researchers from Lund University (Sweden) have investigated the tumor immune microenvironment of primary triple-negative breast cancer using digital image analysis of IHC-stained immune cells. To do ...

Personalized medicine depends on tools, such as immunohistochemistry (IHC), that identify precise targets in a patient’s disease. Immunohistochemistry (IHC) staining is integral in developing ...

Immunohistochemistry protocols, which utilize antibodies to visualize proteins in tissue sections, have many steps that need optimization to prevent nonspecific background effects, artifacts, or ...

Advances in cancer treatment using immunotherapies has accelerated the need to examine the tumor immune microenvironment (TIME). Multiplex immunofluorescence (mIF) assays allow the researcher to ...