When most people think about insulin resistance, sugar is usually the first thing that comes to mind. And while excessive ...

The insulin receptor (IR) is a prototypical receptor tyrosine kinase that orchestrates critical cellular processes, including metabolism, cell growth and differentiation. Activation of the IR involves ...

Insulin is one of the most potent and pleiotropic hormones in the body, regulating a myriad of physiological processes. However, perhaps none is best studied as its role in regulating glucose ...

Adrenomedullin disrupts insulin signaling in blood vessels, leading to systemic insulin resistance in obesity-associated type 2 diabetes, according to a new study by a team at the Max Planck Institute ...

Insulin resistance plays a role in many diseases. The new research provides insights into why insulin resistance appears to be associated with neurodegenerative disorders. Corresponding author Kai ...

Developing resistance to insulin is a key step on the road to diabetes, making insulin resistance a target for treating metabolic dysfunction. Insulin orchestrates blood glucose levels by signaling ...

Insulin resistance precedes and predicts the onset of type 2 diabetes mellitus (DM2), a chronic disease that causes high morbidity and mortality worldwide. In affected people, insulin is unable to ...

Researchers at the University of São Paulo (USP) in Brazil have succeeded in showing, in an animal model, that the process of insulin resistance in the brain affects both Alzheimer’s disease and ...

Q. I don’t have diabetes or pre-diabetes, do you know why my healthcare provider ordered a fasting insulin test?

And it’s true that increasing intake of omega-3-rich foods (like fatty fish) improves cholesterol, triglycerides, blood ...

When lipid biologist Usha Acharya at the National Cancer Institute (NCI) tinkered with lipid breakdown pathways in Drosophila melanogaster, she observed something intriguing. Blocking a biochemical ...

Is fructose the real cause of obesity? A new study explains how fructose metabolism bypasses energy "brakes" and triggers fat ...