Effect on Mean Serum Isoniazid (INH) Bioassay Levels of Raising the Test Dose from 4 to 8 Mg. per Kilogram of Body Weight and of Adding Para-aminosalicylic Acid (PAS) in 46 Patients.

Isoniazid is a prescription drug used to treat tuberculosis (TB). Learn how to lower long-term costs, ... Isoniazid was based on the brand-name drug INH, which is no longer available.

Conclusion . The results of our analysis suggest that INH prophylaxis reduces the risk of TB by 59% among children ≤ 15 years of age, excluding a subset of young children on whom INH was ...

Twelve months of isoniazid (INH) preventive therapy (IPT) significantly reduced the incidence of all TB diagnoses among HIV-positive people who were taking concurrent antiretroviral therapy (ART) ...

INH denotes isoniazid, and TB tuberculosis. The baseline characteristics were generally well-balanced between the two groups ( Table 3 ) in both cohorts. Infants underwent randomization at a ...

Treatment of latent tuberculosis infection (LTBI) generally includes isoniazid (INH), a drug that can cause serious hepatotoxicity. Carboxylesterases (CES) are important in the metabolism of a ...

A 3-month, 12-dose regimen of rifapentine and isoniazid (INH) showed similar efficacy as 6 months of INH alone in preventing tuberculosis in people with HIV, but was less toxic and had better ...

In our 35th year we’re asking people to donate £35 – that’s just £1 for every year we’ve been providing life-changing information. Any donation you make helps us continue our work towards a world ...

Mtb is known for its ability to resist drugs and evade the human immune system. Additionally, multidrug-resistant bacteria have emerged that are resistant to the two most potent TB drugs, isoniazid ...

Prospective randomized, open-label, multiple dose Phase 1 clinical trial This study was designed to evaluate the early and extended early bactericidal activity (EBA) of fluoroquinolone antibiotics ...