Researchers at the Francis Crick Institute have shown that the "pacemaker" controlling yeast cell division lies inside the ...

Gilead Sciences, Inc. (NASDAQ: GILD) and Kymera Therapeutics, Inc. (NASDAQ: KYMR), today announced that they have entered ...

Targeted Oncology connects oncology professionals with updates on immunotherapy, biomarkers, cancer pathways, and targeted ...

A new once-day pill made by AstraZeneca has the ability to delay breast cancer progression in those in the advanced stages ...

Genetic mechanisms of drug resistance. Target Drug(s) Indication(s) Resistance mechanisms Ref. EGFR: Erlotinib: NSCLC: MET amplification, T790M gatekeeper mutation, PTEN loss, HER2 kinase domain ...

If you inhibit this kinase, the forks cannot slow down anymore,” Smolka said. The researchers applied these findings in a model of BRCA2 deficient breast cancer to better understand the ...

Panelists discuss the future of Bruton tyrosine kinase (BTK) inhibitor therapies, considering emerging treatments, regulatory changes, evolving cost dynamics, and the current unmet needs in chronic ...

“The tyrosine kinase inhibitors represent a new mechanism of action where these TKIs — vorolanib, sunitinib and axitinib — actually act intracellularly to act as pan-VEGF, FGF and PDGF ...

Scientists uncover novel immune mechanism in wheat tandem kinase. Chinese Academy of Sciences Headquarters. Journal Science DOI 10.1126/science.adp5469. Keywords ...