Bipolar spindle assembly requires a balance of forces where kinesin-5 produces outward pushing forces to antagonize the inward pulling forces from kinesin-14 or dynein. Accordingly, Kinesin-5 ...

Zachary Gergely, Saad Ansari, Michele Jones, J. Richard McIntosh, and Meredith D. Betterton (2023). Journal of Cell Science136, jcs.260474. DOI: 10.1242/jcs.260474. Download. Kinesin-5 motors are ...

For decades, scientists have known that motor proteins like kinesin-2 ferry vital cargo along microtubule "highways" inside cells. But how these molecular vehicles identify and bind to the right cargo ...

The structure of a key part of the machinery that allows cells to divide has been identified by researchers, opening new possibilities for throwing a wrench in the machine and blocking runaway cell ...

Inside neurons, motor proteins haul precious cargo, moving essential goods along thread-like roadways called microtubule tracks. This miniature highway system is vital for keeping neurons healthy: ...

Zachary Gergely, Ammon Crapo, Loren Hough, J. Richard McIntosh, and Meredith D. Betterton (2016). Molecular Biology of the Cell27, 3490. arXiv DOI: 1604.08134. DOI ...

Biophysicists at Stanford University have finally answered one of the most fundamental questions in molecular biology: How does the tiny motor molecule, known as kinesin, move across a living cell?

Kinesin is the canonical plus-end microtubule motor and has been the focus of intense study since its discovery in 1985. We previously demonstrated a time-dependent inactivation of kinesin in vitro ...

Learn more about an important cellular protein called kinesin from this video by the University of California San Francisco (UCSF), and Ron Vale Ph.D., a UCSF researcher. Kinesin is a motor protein, ...

The structure of a key part of the machinery that allows cells to divide has been identified by researchers at the University of California, Davis -- opening new possibilities for throwing a wrench in ...